List of equipment and methods
Physical and chemical testing:
- Boiling point
- Conductivity
- Densitometry
- Disintegration
- Breaking strength
- Gravimetric tests
- Ash
- Drying loss
- Sulphated ash
- Halogen drying
- Karl-Fischer Titration Ph. Eur. 2.5.12 and 2.5.32
- Melting point
- Osmolality
- Oxygen measurement
- Penetrometer
- pH meter
- Refraction index
- Suppository Penetration Tester
- Breaking strength, diameter, height, mass of dosage forms
- Titration (e.g. potentiometric)
- Viscosimeter
- Visible particles (Ph.Eur. 2.9.20)
- Wet chemistry (Ph. Eur, BP, USP; JP)
- Polarimetry
- Particle counts according to Pharm. Eur. 2.9.19
Dissolution:
- Release USP-I + USP-II + USP-III; (offline) HPLC and UV monitoring
GC systems:
- GC-MS
- GC-EI
- GC-CI
- Headspace-GC-MS
- SPME-GC-MS
HPTLC/TLC:
- Qualitative HPTLC/TLC with photo documentation (UV, VIS, fluorescence)
- Quantitative HPTLC with densitometer
HPLC systems:
- HPLC-DAD
- HPLC-fluorescence
- HPLC-MS/MS (including PAL CTC Autosampler)
- HPLC-RI
- HPLC-UV/VIS
- UPLC-DAD
- UPLC-UV
Mass spectrometry:
- GC-MS (EI/CI)
- Headspace-GC-MS
- SPME-GC-MS
Spectrophotometry:
- FT-IR (ATR and crystal window)
- UV/VIS Spectrophotometer
Stability studies:
- Climatic chambers and climate cabinets (all ICH conditions; special conditions of -80°C up to +55°C)
- Photostability: Atlas Suntester/WUT Stability chamber (ICH Q1B)
Safety weighing enclosures for work with cytostatic and highly active components (SafeTech)
Biological methods:
- ELISA (Non GMP) (Equipment available)
- Capillary electrophoresis (Equipment available)
