List of equipment and methods
Physical and chemical testing:
- Ash
- Boiling point
- Breaking strength
- Breaking strength, diameter, height, mass of dosage forms
- Colorimetry/ color number
- Conductivity
- Densitometry
- Disintegration
- Drying loss
- Gravimetric tests
- Halogen drying
- Karl-Fischer titration acc. to Ph. Eur. 2.5.12 and 2.5.32
- Melting point
- Microscopy
- Non-visible particles (Ph.Eur. 2.9.19)
- Osmolality
- Oxygen measurement
- Particle counts acc. to Pharm. Eur. 2.9.19
- Penetrometer
- pH meter
- Polarimetry
- Refraction index
- Sulphated ash
- Suppository penetration tester
- Titration (e.g. potentiometric)
- Viscosimeter
- Visible particles acc. to Ph.Eur. 2.9.20
- Wet chemistry acc. to Ph. Eur, BP, USP; JP
Dissolution:
- In-vitro dissolution USP-I + USP-II + USP-III; (offline) HPLC und UV-monitoring (Erweka)
GC systems:
- GC-MS
- GC-EI
- GC-CI
- GC-FID
- GC-FID/MS
- Headspace-GC-MS
- Headspace-GC-FID
- SPME-GC-MS
HPTLC/TLC:
- HPTLC/TLC qualitativ with photo documentation (UV, VIS, fluorescence)
- HPTLC quantitativ with densitometer
HPLC systems:
- HPLC-DAD
- HPLC-Fluoreszenz
- HPLC-MS/MS (inklusive PAL CTC Autosampler)
- HPLC-RI
- HPLC-UV/VIS
- UHPLC-MS/MS
- UPLC-DAD
- UPLC-UV
Mass spectrometry:
- GC-MS (EI/CI)
- Headspace-GC-MS
- SPME-GC-MS
- HPLC-MSMS
- UPLC-MSMS
Spectrophotometry:
- FT-IR (ATR and crystal window)
- UV/VIS Spektrophotometer
Stability studies:
- Climatic chambers and climate cabinets (all ICH conditions; special conditions from -80°C up to +55°C)
- Photo stability: Atlas suntester/ WUT stability cabinet (ICH Q1B)
Safety weighing enclosures for work with cytostatic and highly active components (SafeTech)
Biological methods:
- ELISA (Non GMP) (Equipment available)
- Capillary electrophoresis (Equipment available)
